Molecular Infection Biology Laboratory

Exploring microbial membranes to fight resistant infections

Our research group is run by Daniel López at the Spanish National Centre for Biotechnology (CNB). The CNB is the leading research institution at the Spanish National Research Council (CSIC) and is located at the Universidad Autónoma de Madrid (UAM) Campus. In our lab, we use the human pathogen Methicillin-resistant Staphylococcus aureus (MRSA) as a model organism to study the molecular mechanisms underlying the development of bacterial infections. Combining subcellular and multicellular level research, we develop new strategies and antimicrobial therapies to eliminate infectious diseases.

Molecular Infection Biology Laboratory

Exploring microbial membranes to fight resistant infections

Our research group is run by Daniel Lopez at the Spanish National Centre for Biotechnology (CNB), Universidad Autónoma de Madrid (UAM). We use the human pathogen Methicillin-resistant Staphylococcus aureus (MRSA) as a model organism to study the molecular mechanisms underlying the development of bacterial infections. Combining subcellular and multicellular level research, we develop new strategies and antimicrobial therapies to eliminate infectious diseases.

Facing the challenges of antibiotic resistance

We investigate membrane microdomains to understand pathogenic processes

Our laboratory studies bacterial infections by exploring cellular membrane organisation particularly the assembly of Functional Membrane Microdomains (FMMs) in bacterial cells, which we and other laboratories have proven to be critical for virulence and the establishment of infection. We use molecular approaches in combination with advanced imaging techniques like cryo-electron microscopy to uncover the structural and functional complexity of the FMM-associated protein machinery. Our goal is to develop innovative approaches for combating multidrug-resistant infections by targeting FMMs.

Facing the challenges of antibiotic resistance

We investigate membrane microdomains to understand pathogenic processes

Our laboratory studies bacterial infections by exploring cellular membrane organisation particularly the assembly of Functional Membrane Microdomains (FMMs) in bacterial cells, which we and other laboratories have proven to be critical for virulence and the establishment of infection. We use molecular approaches in combination with advanced imaging techniques like cryo-electron microscopy to uncover the structural and functional complexity of the FMM-associated protein machinery. Our goal is to develop innovative approaches for combating multidrug-resistant infections by targeting FMMs.

The MIB lab team

We bring together expertise from molecular biology to structural and infection biology.