Meet the team
We are experts in molecular infection biology
TeamD3veloperSCS_m1bl4b2024-02-26T08:29:08+00:00
Meet the team
We are experts in molecular infection biology
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Since 2010, I have led an independent laboratory, first as Young Group Leader at the University of Würzburg (2010-2015, Germany) and currently as tenured Principal Investigator at Spanish National Research Council CNB-CSIC (2015, Spain). Before becoming Young Investigator, I was a postdoctoral fellow at Harvard Medical School (2006-2010, USA) and a predoctoral fellow at University of Murcia (2000-2005, Spain). Throughout my career, I have specialized in microbiology, molecular genetics, molecular biology and biochemistry. Now, I apply this scientific background to lead my laboratory into the exploration of membrane microdomains and other processes for cellular compartmentalization in bacteria, their contribution to pathogenesis and the design novel strategies against antibiotic-resistant bacterial infections.
I graduated at Complutense University and completed my Ph.D. in Immunology and Molecular Biology at Autonomous University of Madrid (2009, Spain). At 2010, I started working at the Immunology department of the CNB to understand the molecular mechanisms responsible for the response of the immune system against microbial infections. In 2020, I joined the MIB lab to investigate the role of bacterial membrane microdomains to bacterial pathogenesis during an infection. I also contribute with my knowledge of the immune system’s response to assist to other lab members to implement in vivo or in vitro infection experiments for their research projects.
I graduated and obtained my Ph.D. in biochemistry and Molecular Biology at the Autonomous University of Madrid (2001, Spain). I joined the CNB after a postdoctoral period at the Severo Ochoa Centre for Molecular Biology (CBMSO). My professional career revolves around understanding the assembly of multiprotein complexes in bacteria and elucidating the role of these machineries in bacterial physiology using molecular techniques and fluorescence microscopy approaches. Now at the MIB lab, I explore the organization of multiprotein complexes in the membrane microdomains of pathogenic bacteria and how they can be used as targets to design innovative approaches to fight antibiotic-resistant infections. I also assist other lab members to design and perform molecular approaches for their research projects.
I graduated in Biology and obtained a Master degree at the Complutense University (2016, Spain). I am specialized in protein production and purification, in diverse DNA cloning and recombineering techniques, as well as in in vivo infection assays. At the MIB lab, I apply my experience in protein purification to assist in projects related to structural biology. I contribute with cloning and recombineering to implement diverse molecular techniques and assist in projects that involve in vivo infection experiments. Furthermore, I am responsible for the general organization and correct functioning of the laboratory techniques.
During my Ph.D. at the Institute of Biochemistry and Biophysics at Warsaw (2015, Poland) and a postdoctoral period at University College of London (2015-2017, UK) I specialized in Structural Biology before I joined the MIB lab in 2017. Now at the MIB lab, I am a Juan de la Cierva postdoctoral fellow, and I use cryo electron microscopy in combination to molecular biology approaches to investigate the structure of proteins and complexes to understand the mechanisms of cellular machineries. I operate along the entire workflow, from hands-on laboratory work in protein purification and sample preparation to implementing imaging approaches using cryo EM and finally to generate 3D reconstructions using computational methods.
I obtained my PhD at the Complutense University and the Joined Centre for Biological Research (CIB-CSIC) on steroid transport in Mycobacterium species and its potential biotechnological applications (2015, Spain). During my Ph. D., I specialized in molecular biology applied to microorganisms, which now I use at the MIB lab, to explore potential biomedical and biotechnological applications of bacterial membrane microdomains. I am fascinated by exploring the mechanisms that bacteria use to adapt to challenging environmental conditions, and how this knowledge could improve industrial bioprocesses
I obtained a Master and a Ph. D. in Molecular Biology and Biotechnology at the University of Murcia (2020, Spain). During my PhD, I studied the production of plasmalogen lipids in response to light in the soil bacterium Myxococcus xanthus. Now at the MIB lab, I am a Juan de la Cierva postdoctoral fellow. I use my expertise in Molecular Biology and Gene Regulation to explore the role of functional membrane microdomains in the pathogenesis and antibiotic resistance profile of human pathogen Staphylococcus aureus. I also explore the evolutionary response of this pathogen to defective membrane microdomains for the pathogen survival during infection.
I graduated in Biothecnology and bioinformatics at the Extremadura University before I obtained a Master degree in Computational Biology at Polytechnic University of Madrid (2021, Spain). I started my Ph.D. at the MIB lab in 2022 holding a Ph.D. scholarship funded by the Spanish National Government (FPU). My Ph.D. project is focused on applying the computational advances that are currently offered by artificial intelligence and deep-learning methods to better understand the bacterial processes related to the development of infections.
I obtained a B.Sc in Molecular Biology at Alcalá de Henares university and a Master in Microbiology Applied to Public Health and Infectious Diseases at the Institute of Health Carlos III (2021, Spain). My previous studies have focused on identifying the genetic mechanisms involved in the dispersion of antibiotic resistance genes in hospital-isolated pathogenic bacteria. In 2022, I obtained a Ph.D. scholarship from the Regional Government of Madrid to join the MIB Lab. In my Ph. D. project, I apply genetics and molecular biology approaches to describe a new mechanism that confer resistance to antibiotics in clinical isolates of MRSA and I design new targeting strategies against mechanism to eliminate MRSA infections.
I become interested in microbiology at my B. Sc. in Biology and my M. Sc. in Microbiology and Parasitology at the Complutense University. After this, I joined the MBI lab to do my Ph. D thesis in molecular microbiology. In my thesis, I explore the cellular processes that are associated with the assembly of bacterial membrane miocrodomains. To do this, I use a combination of molecular biology techniques to super-resolution fluorescence microscopy approaches. In my studies, I am showing that bacteria more sophisticated organisms than previously thought.
I studied a B.Sc. in Biology at the Alcalá University before obtaining a M. Sc. in Biotechnology at Autonomous University of Madrid (2017, Spain). During my Ph. D. at the MIB lab, I investigate the mechanisms that control the production of the constituent proteins of the bacterial membrane microdomains. My project is focused on Gram-negative organisms and more specifically on the human pathogen Pseudomonas aeruginosa. I have established different molecular techniques for Pseudomonas genetic manipulation, such as CRISPR-Cas. I use these techniques to describe the protein-protein interactions that license the production of membrane microdomain proteins, how this regulatory system respond to infection signals and thus how relevant is to the establishment of Pseudomonas infections.